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Resident tissue macrophages transfer selenium transporter protein to protect pancreatic cancer from ferroptosis.

Wei Guo, Ziyi Li, Qihan Chen, Garett Dunsmore, Li Jiang, Zhijie An, Ziwen Fu, Yibo Liu, Yufei Shao, Shulin Zhao, Ting Wang, Huan Tang, Chengjian Zhao, Guangyan Zhangyuan, Jia Liu, Pengyi Liu, Zhaoyuan Liu, Jiawen Qian, Shuangyan Zhang, Minmin Shi, Ding He, Yedan Liu, Camille Blériot, Lai Guan Ng, Fan Bai, Lingxi Jiang, Bing Su, Baiyong Shen, Florent Ginhoux

CellSep 24, 2026PMID 42785301doi:10.1016/j.cell.2026.09.001 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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Pancreatic ductal adenocarcinoma (PDAC), an aggressive cancer with a poor prognosis, contains resident tissue macrophages (RTMs) present before tumor onset and monocyte-derived macrophages recruited during tumor development, but their distinct roles in supporting tumor progression remain unclear.…

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