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Long-term Endoscopic Surveillance in Hereditary Diffuse Gastric Cancer Syndrome.

Muhan Li, Danielle Lynch, Tanushka Dewan, Kajal Patel, Devanshi Patel, Daniel C Chung

Cancer prevention research (Philadelphia, Pa.)Sep 24, 2026PMID 42784746doi:10.1158/1940-6207.CAPR-26-0102 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 29, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260929-000001
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Hereditary Diffuse Gastric Cancer (HDGC) syndrome arises from a germline variant in CDH1 and is characterized by a high risk of gastric signet-ring cell carcinoma. Total gastrectomy is the most definitive strategy for cancer risk reduction but carries high morbidity. Endoscopic surveillance is an…

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