Publication
Cytotoxic Microspinosamides from the Marine Sponge Geodia microspinosa That Decrease Diffuse Pleural Mesothelioma Viability.
Maria Orfanoudaki, Dongdong Wang, Lin Du, Vivek Singh, Ekaterina I Goncharova, Nathanael Pruett, Chuong D Hoang, Brice A P Wilson, Barry R O'Keefe
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- PubMed
- Retrieved
- Sep 30, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260930-000001
Abstract
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A fraction from an extract of the marine sponge Geodia microspinosa was identified as active in a high-throughput screen for molecules that impair the viability of diffuse pleural mesothelioma (DPM) cell lines. Bioassay-guided isolation led to the identification of microspinosamides B and D, and a…
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- cancerMalignant Mesotheliomadictionary0.60
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