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Anorectal substructure dosimetry and low anterior resection syndrome after neoadjuvant radiotherapy for rectal cancer: an exploratory analysis.

Fabrizio Sanna, Daniele Delogu, Maria Chiara Ninniri, Giulia Deiana, Elena Pisanu, Angela Pia Solazzo, Grazia Lazzari, Salvatrice Campoccia

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]Sep 24, 2026PMID 42782287doi:10.1007/s00066-026-02602-4 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
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Low anterior resection syndrome (LARS) is a frequent complication after sphincterpreserving surgery for rectal cancer, often exacerbated by neoadjuvant radiotherapy. While radiotherapy is a recognized risk factor, the specific contribution of dose to anorectal substructures remains unclear. This…

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