Publication
IGF2BP3 remodels RISC occupancy to control microRNA targeting in leukemia.
Lyna E S Kabbani, Shruti Kapoor, Gunjan Sharma, Martin Gutierrez, Zachary T Neeb, Amit K Jaiswal, Alexander J Ritter, Sol Katzman, Jordyn E Feldman, Dinesh S Rao, Jeremy R Sanford
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- PubMed
- Retrieved
- Sep 30, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260930-000001
Abstract
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IGF2BP3 is an oncofetal RNA-binding protein that promotes leukemogenesis, but the mechanisms by which it remodels post-transcriptional gene regulation remain incompletely understood. Because IGF2BP3 binds extensively within 3' untranslated regions and has been implicated in microRNA…
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- cancerLeukemiadictionary0.60
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