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Domain-generalizable oral cancer classification: bridging multi-center histopathological datasets.

Ziying Hua, Yushi Zhou

Frontiers in medicineJan 1, 2026PMID 42780371doi:10.3389/fmed.2026.1951350 PMC13597261Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
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Deep models for oral squamous cell carcinoma (OSCC) detection from haematoxylin-eosin histopathology degrade sharply across laboratories, scanners and magnifications, yet the target centre is usually unavailable during training, making generalization to unseen domains the decisive requirement for…

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