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The spatiotemporal ecosystem of gallbladder cancer: From inflamed areas to invasive margins - Integrating biomechanical injury, the bile microenvironment, precursor lineages, and spatial niches.

Qingyang Meng, Houbao Liu

Bioscience trendsSep 22, 2026PMID 42778405doi:10.5582/bst.2026.01237 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
Published

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Gallbladder cancer (GBC) is usually described as the end point of chronic cholelithiasis-associated inflammation, and yet this linear formulation does not explain why only a small fraction of people with gallstones develop cancer, why histologically similar precursor lesions follow different…

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