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Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma.

Matthew J Frigault, Binod Dhakal, Andrzej J Jakubowiak, Noopur Raje, Kamalika Banerjee, C Jenny Mu, Kevin C Hart, Sigal Shachar, Lawrence P Andrews, Laurene S Cheung, Faith M Griffin, Alexandra R Witter, Michael Hyde, Chester Pham, Nikitha Gandra, Tenzin Shakya, Bhargavi Rajan, Christa Cortesio, Samuel T Haile, Heba Nowyhed, Priyanka Nair-Gupta, Priyam Mitra, Rebecca J Chan, Ana Kostic, Christopher R Heery, Jacalyn Rosenblatt, Michael R Bishop

The New England journal of medicineSep 24, 2026PMID 42777241doi:10.1056/NEJMoa2603527 Journal ArticleClinical Trial, Phase IMulticenter StudypubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
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BACKGROUND: Anitocabtagene autoleucel (anito-cel), a B-cell maturation antigen (BCMA)-directed autologous chimeric antigen receptor (CAR) T-cell therapy with a synthetic d-domain binder (ddBCMA), may have efficacy in patients with relapsed or refractory multiple myeloma. METHODS: In a phase 1…

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Registered trialsNCT04155749

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