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Current Landscape of RAS-Targeted Therapy for Pancreatic Cancer.

Y Linda Wu, Benjamin Herzberg, Gulam A Manji

The oncologistSep 23, 2026PMID 42776617doi:10.1093/oncolo/oyag379 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 29, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260929-000001
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Pancreatic ductal adenocarcinoma (PDAC) continues to carry a poor prognosis, and only incremental gains in systemic therapy have been made over the past decade. Because activating KRAS mutations are present in more than 90% of PDAC and serve as the inciting oncogenic driver, RAS has long been a…

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