Publication
Carmofur inhibits ovarian cancer cell proliferation, migration, and invasion via disrupting the YAP-1/TEAD pathway: in vitro and in silico approaches.
Celal Cengiz, Canan Vejselova Sezer, Bahri Gür, Hatice Mehtap Kutlu, Adnan Ayhanci, Nuri Bakan, Alpaslan Bayrakdar, Mustafa Cengiz
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- PubMed
- Retrieved
- Sep 29, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260929-000001
Abstract
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The current study aims to present a novel approach to alleviate the aggressiveness of ovarian cancer by pharmacological disruption of the Yes-Associated Protein (YAP) - 1/Transcriptional Enhancer Factor domain (TEAD) heterodimer structure using Carmofur. The Ovcar-3 cell line was incubated with…
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- cancerMalignant Ovarian Neoplasmdictionary0.60
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