Publication
Genetic evaluation of encorafenib-associated kinases RAF1 and MAPK8 in pancreatic cancer: Exploratory mediation by circulating immune traits.
Fen Lin, Wenwen Tu, Ronggui Lin, Han Shi, Shiyun Lu, Zongqi Weng
Translational oncologySep 22, 2026PMID 42771912doi:10.1016/j.tranon.2026.103040 Journal ArticlepubmedProvenance
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- Sep 29, 2026
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Abstract
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OBJECTIVES: Pancreatic cancer (PC) is a highly lethal malignancy, and identifying actionable therapeutic targets remains crucial. RAF1 and MAPK8 are kinases linked to the in vitro pharmacological profile of encorafenib. This study investigated the associations of genetically proxied RAF1 and MAPK8…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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