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Elucidating the potential anti-liver cancer mechanisms of the medicinal food Rosa roxburghii Tratt. by integrating HPLC-Q Exactive MS/MS, network pharmacology, and in vitro validation.

Miao Zeng, Huifang Chai, Yongjia Shu, Min Liu, Danli Wang, Tian Lu

Natural product researchSep 22, 2026PMID 42771809doi:10.1080/14786419.2026.2736642 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
Published

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This study integrated HPLC-Q Exactive Plus MS/MS analysis, network pharmacology, molecular docking, and in vitro assays to investigate the anti-liver cancer mechanisms of flavonoid components from Rosa roxburghii Tratt. (RRT) ethanol extract. A total of 52 flavonoids were identified, including 15…

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