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Upfront surgery vs. neoadjuvant therapy in pancreatic cancer with venous involvement: a multicenter retrospective analysis.

Asif Halimi, Eline S Zwart, Bengi S Yilmaz, Benediktas Kurlinkus, Reea Ahola, Marco Del Chiaro, Ernesto Sparrelid, Elena Rangelova, Laura Maggino, Giuseppe Malleo, Gabriella Lionetto, Roberto Salvia, Keith J Roberts, Francesco Giovinazzo, Massimo Falconi, Stefano Crippa, Giulio Belfiori, Geert Kazemier, Patrick Maisonneuve, Johanna Laukkarinen, Güralp O Ceyhan

Langenbeck's archives of surgerySep 22, 2026PMID 42771072doi:10.1007/s00423-026-04291-0 PMC13597592Comparative StudyJournal ArticleMulticenter StudyObservational StudypubmedProvenance
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PubMed
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Sep 28, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260928-000001
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INTRODUCTION: The benefits of neoadjuvant therapy (NAT) for pancreatic cancer (PC) with portal venous involvement remain debated. This study aimed to compare the short- and long-term outcomes of surgery with or without NAT in patients with PC with suspected venous involvement. METHODS: A…

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