Publication
Complement factor B blockade by iptacopan drives antitumor complement-based immunomodulation in pancreatic cancer microenvironment.
Daren Zhou, Shigetsugu Takano, Kazuyuki Sogawa, Ryo Moriyasu, Tsukasa Takayashiki, Daisuke Suzuki, Nozomu Sakai, Masayuki Ohtsuka
- Source
- PubMed
- Retrieved
- Sep 26, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260926-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Recent advanced comprehensive analyses reveal complement factors as critical regulators of cancer-immune system interactions. We previously identified that complement factor B (CFB), a key secreted component of the alternative complement pathway, is aberrantly upregulated in pancreatic ductal…
Read on PubMedLinked entities
Linked entities (1)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Candidate 1
- cancerMalignant Pancreatic Neoplasmdictionary0.60
Curated evidence
Evidence citing this paper (0)
Data not yet available