Publication
Ultrasound radiomics integrated with an immune-related gene signature for predicting response and resistance to immune checkpoint inhibitors in cutaneous melanoma: a retrospective radiogenomic study with biological validation.
Jinyu Peng, Bowen Dai, Kan Ze, Jie Yang
Frontiers in geneticsJan 1, 2026PMID 42765081doi:10.3389/fgene.2026.1920615 PMC13590222Journal ArticlepubmedProvenance
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- Sep 30, 2026
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Abstract
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BACKGROUND: Immune checkpoint inhibitors (ICIs) have transformed cutaneous melanoma therapy, yet 50% of patients show primary or acquired resistance, and current biomarkers (PD-L1 and tumor mutational burden) lack precision. High-frequency ultrasound (HFUS), contrast-enhanced ultrasound (CEUS), and…
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- cancerCutaneous Melanomadictionary0.60
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