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ADORA1 inhibition suppresses colon cancer development via hippo tumor suppressor pathway.

Zhongbo Li, Zhihao Liu, Xiaobo Zhang, Zhuocong Bao, Xiujie Cui, Xin Li, Jiayao Cui, Fangyu Shen, Yan Zhou, Pengzhao Song, Lin Ma, He Li, Hanxue Zhang, Haidi Hu, Ting Zhuang, Xiaodong Tan, Jian Zhu

Cell death and differentiationSep 19, 2026PMID 42763325doi:10.1038/s41418-026-01860-0 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
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Coffee is one of the most commonly consumed beverages in daily life, with caffeine being the major psychoactive component that acts against fatigue and drowsiness. Epidemiological studies have demonstrated the protective effect of coffee intake on colon cancer risk, recurrence and overall survival,…

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