Publication
PAX9 activates autophagy through a transcription-dependent mechanism, promoting EGFR degradation to restrict cell survival in oral cancer.
Chandra Sekhar Bhol, Rakesh Kumar Kar, Soumya Ranjan Mishra, Priyadarshini Mishra, Kewal Kumar Mahapatra, Xi Zhang, Samir Kumar Patra, Shankargouda Patil, Gautam Sethi, Daniel J Klionsky, Peter E Lobie, Vijay Pandey, Sujit Kumar Bhutia
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- PubMed
- Retrieved
- Sep 29, 2026
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- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260929-000001
Abstract
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BACKGROUND: PAX9 (paired box 9) gene, a transcription factor belonging to the PAX family, is associated with craniofacial development. Dysregulation of PAX9 is associated with oral squamous cell carcinoma (OSCC), and its functional regulation in OSCC remains unknown. METHODS: PAX9 expression was…
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- cancerMalignant Lip and Oral Cavity Neoplasmdictionary0.60
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