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CD147-SNAP-tag-CMC/HPLC-MS two-dimensional coupling system: a universal platform for screening active components targeting CD147 for anti-liver cancer applications.

Wenhao Chen, Haoyun Bai, Quan Zhang, Jingjing Yang, Shengyu Zhou, Du Feng, Shengli Han

Journal of chromatography. B, Analytical technologies in the biomedical and life sciencesSep 17, 2026PMID 42762798doi:10.1016/j.jchromb.2026.125294 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 28, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260928-000001
Published

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Hepatocellular carcinoma (HCC) is one of the most prevalent digestive malignancies, with CD147 emerging as a promising therapeutic target for HCC. To date, no natural bioactive components targeting CD147 for anti-HCC therapy have been explicitly reported. Given the low toxicity and favorable…

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