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Plasma cfDNA fragmentomics enables non-invasive detection and preoperative risk stratification of bladder cancer in a multicenter study.

Kaihua Liu, Hua Bao, Guangqi Li, Wenwen Ran, Ping Yang, Zongliang Zhang, Wenxian Li, Ningyou Li, Minhui Ren, Tao Ding, Peng He, Shanshan Yang, Xinyue Hong, Ke Wang, Xiaoming Xing

Cancer lettersSep 18, 2026PMID 42759922doi:10.1016/j.canlet.2026.218853 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 26, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260926-000001
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Accurate non-invasive tools for bladder cancer detection and preoperative assessment of muscle invasion remain limited. We developed a plasma cell-free DNA (cfDNA) fragmentomics assay to support two clinically related tasks: detection of bladder cancer and preoperative estimation of muscle-invasive…

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