Publication
Molecular reprogramming in cutaneous melanoma: the central role of G9a and EZH2 methyltransferase inhibitors in tumor plasticity, immune evasion, and therapeutic resistance.
Melissa Yoshimi Sakamoto Maeda Nisimoto, Daniel Arcuschin de Oliveira, Heitor Raia Bottura, Wagner Robson Germano Sousa, Gabrielle do Nascimento Sividanes, Amanda Fáris Marques, Jaciara Moreira Sodré Hunnicutt, Alexandre Giannecchini Romagnolo, Maria Clara Ferreira Vivi, Beatriz Linhares Gorini, Francisco Macedo Paschoal, Miguel Sabino Neto, Miriam Galvonas Jasiulionis, Luciana Cavalheiro Marti, Renato Santos de Oliveira Filho
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- PubMed
- Retrieved
- Sep 30, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260930-000001
Abstract
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Cutaneous melanoma remains a leading cause of skin cancer-related mortality despite significant therapeutic advances, with treatment resistance and immune evasion representing major clinical challenges. Epigenetic dysregulation, particularly through the histone methyltransferases G9a (EHMT2) and…
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Candidate 1
- cancerCutaneous Melanomadictionary0.60
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