Publication
Tumor FAK supports fibrillar collagen expression in ovarian cancer ascites.
Marjaana Ojalill, Terrance J Haanen, Safir Ullah Khan, Yichi Zhang, Antonia Boyer, Xiao Lei Chen, Ujjwal Suwal, Pekka Rappu, Jyrki Heino, Michael T McHale, Dwayne G Stupack, David D Schlaepfer
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- PubMed
- Retrieved
- Sep 19, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260919-000001
Abstract
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High-grade serous ovarian cancer (HGSOC) is a lethal malignancy where matrix proteins enhance ascites-associated recurrent tumor growth. Elevated focal adhesion kinase (FAK/PTK2) and collagen protein expression support tumor survival, chemoresistance, and immune evasion. However, the sources and…
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- cancerMalignant Ovarian Neoplasmdictionary0.60
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