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Outcomes of down syndrome-related myeloid leukemia in Turkiye: a multicenter retrospective observational cohort study by the Turkish Pediatric Hematology Association.

Yeter Düzenli Kar, Hale Ören, Melike Sezgin Evim, Emine Zengin, Ekin Gün, Nihal Karadaş, Deniz Yılmaz Karapınar, Canan Albayrak, Selma Ünal, Feryal Karahan, Murat Söker, Veysiye Hulya Uzel, Arzu Akyay, Yurday Öncül, Ayşenur Bahadır, Mehmet Fatih Orhan, Suar Çakı Kılıç, Burcu Tufan Taş, Elif Güler Kazancı, Betül Orhaner, Tuba Hilkay Karapınar, Yusuf Ziya Aral, Neşe Yaralı, Ali Fettah, Güven Özkaya, Adalet Meral Güneş

Annals of hematologySep 15, 2026PMID 42752662doi:10.1007/s00277-026-07245-0 PMC13585845Journal ArticleMulticenter StudyObservational StudypubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
Published

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Children with Down syndrome (DS) have a 150-times increased risk of myeloid leukemia (ML). In DS patients, in addition to DS-ML, common acute myeloid leukemia (AML) subtypes (standard-AML), observed in patients without DS, may also be seen. We evaluated ML types developing among DS cases, along…

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