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X‑ray FLASH RT inhibits lung cancer bone metastasis via activating CD4⁺ T-cell‑mediated antitumor immunity with modulation of Th17 cell response.

Yao Huang, Tao Wu, Wen Yang, Yuan-Yuan Liang, Yun-Fei Sun, Chao-Fan Ma, Ruo Tang, Rui-Ci Liang, Xue-Ting Zheng, Hui-Wen Luo, Cheng-He Ding, Xiao-An Li, Yan Zhou

OncoimmunologyDec 31, 2026PMID 42752269doi:10.1080/2162402X.2026.2706271 PMC13596902Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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Lung cancer is characterized by rapid progression and poor prognosis, with 50%-70% of patients presenting local or distant metastasis at diagnosis, among which bone metastasis is the most common type. Radiotherapy is the standard approach for managing cancerous bone metastasis pain. Here, we report…

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