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EML4::RET, a novel transcript fusion in papillary thyroid cancer.

Renaud Ciappuccini, Raphaël Leman, Laurent Castera, Marine Dorbeau, Véronique Le Hénaff, Stéphane Bardet

JCEM case reportsOct 1, 2026PMID 42751117doi:10.1210/jcemcr/luag272 PMC13579062Case ReportsJournal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
Published

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Fusion genes are the most common genetic alterations found in pediatric papillary thyroid cancers (PTCs). Pediatric PTCs harboring fusion genes are generally associated with more aggressive disease than those without. RET (rearranged during transfection) rearrangements are the most common fusion…

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