Publication
Maslinic acid derivative induces the death of transitional bladder cancer cells through apoptosis and autophagy via the PI3K-AKT signaling pathway.
Jing-Jing Liu, Li Sun, Dan-Ting Guo, Yu-Jie Liang, Li-Qiong Zhang, Jun-Ji Chen, Quan-de Wang, Ke-Guang Cheng
RSC medicinal chemistrySep 16, 2026PMID 42751009doi:10.1039/d6md00435k PMC13579370Journal ArticlepubmedProvenance
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- PubMed
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- Sep 26, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260926-000001
Abstract
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l-Phenylalanine and l-glutamine were conjugated with maslinic acid and 3-epi maslinic acid to generate 16 derivatives. Most of them exhibited higher cytotoxic activity than maslinic acid towards various tumour cell lines. Based on the results from the human apoptosis array and western blotting…
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- cancerMalignant Bladder Neoplasmdictionary0.60
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