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Longitudinal gut microbiome dynamics during immunotherapy identify microbial features of clinical benefit in advanced primary liver cancer.

Zhenwei Qian, Jie Han, Beile Lyu, Aizier Ainiwaer, Qiancheng Zhao, Shuai Wang, Jiamin Cheng, Yinyin Li, Ying Sun, Xiannian Zhang, Yinying Lu

GutSep 16, 2026PMID 42749361doi:10.1136/gutjnl-2026-339115 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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BACKGROUND: The gut microbiome has been linked to immune checkpoint inhibitor (ICI) outcomes, but the temporal dynamics of microbial communities during treatment remain poorly characterised. OBJECTIVE: To characterise gut microbiome trajectories during ICI therapy and evaluate whether on-treatment…

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