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Integrated analysis of VEGFA rs833061 (- 460T > C) promoter polymorphism and serum YKL-40 levels in bladder cancer: evidence of a genotype-phenotype association.

Rohit Kaushik, Devender Pawar, Anuradha Sharma, Kiran Siwach, Gulshan Rohilla, Sonia Narwal, Nisha Khatri, Ankit Arora, Minakshi Vashist

Molecular biology reportsSep 16, 2026PMID 42747566doi:10.1007/s11033-026-12776-w Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 19, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260919-000001
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BACKGROUND: Angiogenesis plays a central role in bladder cancer progression. VEGFA regulates angiogenesis, whereas YKL-40 is a pro-angiogenic biomarker. The relationship between VEGFA polymorphism and circulating YKL-40 remains unclear. METHODS AND RESULTS: A hospital-based case-control study…

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