Publication
PRMT1-Mediated Arginine Methylation Redirects SMAD4 Signaling to Promote Metastasis in Pancreatic Cancer.
Yizhou Liu, Xueyi Liang, Ruozheng Wei, Yu Peng, Gengdu Qin, Jiaying Liu, Yuhan Zhao, Hongkun Cai, Taoyu Chen, Shanmiao Gou, Tao Yin, Bo Wang, Heshui Wu, Yingke Zhou
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- PubMed
- Retrieved
- Sep 19, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260919-000001
Abstract
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Pancreatic ductal adenocarcinoma (PDAC) is characterized by early metastatic dissemination and poor clinical outcomes. Although SMAD4 is frequently altered in PDAC, the majority of tumors retain wild-type SMAD4, which paradoxically acquires pro-metastatic functions during disease progression.…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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