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Tri-modal PSMA PET/CT-MRI-US fusion biopsy for clinically significant prostate cancer: a prospective paired diagnostic study.

Chen Huang, Lichen Jin, Yizhang Sun, Menglin Wu, Xuefeng Zhang, Xiaofeng Xu, Xuefeng He, Feng Qiu, Ximing Wang, Lingchuan Guo, Renpeng Huang, Jihui Li, Shengming Deng, Yuxin Lin, Xuedong Wei, Bin Zhang, Yuhua Huang

European journal of nuclear medicine and molecular imagingSep 15, 2026PMID 42742683doi:10.1007/s00259-026-08181-x Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 16, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260916-000001
Published

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PURPOSE: Multiparametric MRI (mpMRI)-ultrasound (US) fusion biopsy misses 8%-20% of clinically significant prostate cancer (csPCa), leaving a detection gap that prostate-specific membrane antigen (PSMA) PET/CT may help close. Whether incorporating PSMA into an MRI-US fusion platform improves csPCa…

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