Publication
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells.
Lucy E Bonilla, Martín M Ledesma, Santiago A Behr, Matías A Pibuel, María L Palanek, Daniel H Grasso, Maria N Garcia, Juan Garona, Silvina L Lompardía, Elida Álvarez, Daniela L Papademetrio
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- PubMed
- Retrieved
- Sep 19, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260919-000001
Abstract
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Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy characterized by poor prognosis and limited response to gemcitabine, the standard first-line chemotherapy. One major contributor to chemoresistance is autophagy, a process frequently upregulated in PDAC. In this study, we examined…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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