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Esomeprazole inhibits EGF-induced invasion and migration of gastric cancer cells.

Fangfang Huang, Jinfeng Du, Xuanruo Zhang, Mengru Tian, Qiangqiang Lv, Xiufeng Chu, Hongqiao Zhang, Zisen Zhang

PeerJJan 1, 2026PMID 42741692doi:10.7717/peerj.21675 PMC13573768Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 16, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260916-000001
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BACKGROUND: Gastric cancer (GC) is one of the most prevalent and lethal malignancies worldwide, with invasion and metastasis being the key factors contributing to its poor prognosis and high mortality rates. Epidermal growth factor (EGF)-induced activation of EGFR and downstream AKT/mTOR signaling…

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