Publication
ARNTL2 promotes metastatic phenotypes through SERPINE1 transcription in KRAS G12D pancreatic cancer.
Xiaohan Shi, Xiaoyi Yin, Suizhi Gao, Xinqian Wu, Huan Wang, Beilei Wang, Xiongfei Xu, Kailian Zheng, Wei Jing, Gang Li, Shiwei Guo, Gang Jin
- Source
- PubMed
- Retrieved
- Sep 19, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260919-000001
Abstract
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Despite the prevalence of the KRAS G12D mutation in approximately 40% of pancreatic ductal adenocarcinoma (PDAC) cases and its association with the poorest prognosis among KRAS variants, the downstream transcriptional effectors driving its aggressive metastatic phenotype remain poorly defined.…
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Candidate 1
- cancerMalignant Pancreatic Neoplasmdictionary0.60
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