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Clinicopathologic Spectrum and Intraprostatic Heterogeneity of Primary Mismatch Repair-Deficient Prostate Cancer.

Darrell Martin, Carol C Cheung, Chen Yang, Léonie Beauchamp, Mehdi Mansoor, Sophia M Green, Shamini Selvarajah, Susan Prendeville

The American journal of surgical pathologySep 15, 2026PMID 42740602doi:10.1097/PAS.0000000000002623 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 16, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260916-000001
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Mismatch repair deficiency (MMRd) is identified in a small subset of prostate cancers and has implications for therapy selection and germline testing. The clinicopathologic spectrum of primary MMRd prostate cancer remains incompletely characterized. We evaluated 32 primary treatment-naive MMRd…

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