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Integrated Pharmacogenomic and Structure-Guided Analyses Link LCC-10 (NSC765599) to an MMP-Associated Extracellular Matrix Regulatory Network in Leukemia.

Han-Lin Hsu, Tawakalitu Bidemi Aliu, Ya-Ting Wen, Yu-Cheng Kuo, Li Wei, Ruey-Shyang Soong, Maryam Rachmawati Sumitra, Sheng-Liang Huang, Shih-Yu Lee, Sung-Ling Tang, I-Chuan Yen, Hong-Jaan Wang, Bashir Lawal, George Hsiao, Alexander T H Wu, Hsu-Shan Huang

CellsSep 4, 2026PMID 42738903doi:10.3390/cells15171610 PMC13564721Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
Published

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Leukemia progression is increasingly shaped by reciprocal interactions between leukemic cells and the bone marrow microenvironment, yet the extracellular regulatory networks associated with these interactions remain incompletely understood. Here, we investigated the biological context associated…

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