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Identification of Factors That Determine Adherence for Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer.

Cynthia Araradian, Emmett Hunnicutt, Siting Chen, Shawna Rivedal, Shelby Willis, Maura Walsh, Vassiliki Liana Tsikitis, Sandy Hwang Fang

CancersSep 3, 2026PMID 42738373doi:10.3390/cancers18172853 PMC13564784Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 16, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260916-000001
Published

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Background: Locally advanced rectal cancer (LARC) treatment has shifted from the utilization of neoadjuvant chemoradiation (NACRT), followed by total mesorectal excision (TME) and adjuvant chemotherapy (AC) to the implementation of total neoadjuvant therapy (TNT). This transition was influenced by…

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