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Detachment-induced ETS1 drives anoikis resistance and metastasis through STX3-mediated PTEN ubiquitination in gastric cancer.

Pengbo Hu, Lin Fu, Yujun Wu, Yongping Lian, Yongqing Liu, Fangyuan Zhang, Yifan Fu, Yuhong Dai, Liang Xu, Hong Qiu

Biochimica et biophysica acta. Molecular basis of diseaseSep 14, 2026PMID 42735835doi:10.1016/j.bbadis.2026.168464 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 17, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260917-000001
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BACKGROUND: Anoikis resistance enables detached gastric cancer cells to survive during metastasis. However, the transcriptional mechanisms that sustain survival signaling under detachment stress remain incompletely understood. METHODS: Public transcriptomic and single-cell datasets, patient-derived…

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