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Integrated Analysis of HER2 Expression and ERBB2 Alterations in Bladder Cancer.

Kensuke Hirosuna, Kazuki Nishimura, Moritoshi Sakamoto, Satoshi Tokushige, Keita Nakamori, Tomohisa Matsunaga, Yuki Yoshikawa, Takeshi Tsutsumi, Ryoichi Maenosono, Takuya Tsujino, Masahiko Ajiro, Haruhito Azuma, Akihide Yoshimi, Kazumasa Komura

Cancer scienceSep 13, 2026PMID 42732768doi:10.1111/cas.70534 PMC13571850Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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Human epidermal growth factor receptor 2 (HER2) has emerged as a potential therapeutic target in bladder cancer (BC), particularly with the advent of next-generation antibody-drug conjugates (ADCs) like trastuzumab deruxtecan (T-DXd). However, the complex relationship between HER2 protein…

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