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Acrylamide-associated gastric cancer progression involves RRM2-related nucleotide metabolic dysregulation and immune evasion.

Peiru Si, Tianlong Zhang, Xuefeng Lv

Translational oncologySep 12, 2026PMID 42732660doi:10.1016/j.tranon.2026.103036 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 16, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260916-000001
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Acrylamide (AA) is a widespread environmental contaminant and a probable human carcinogen. Its role in gastric cancer (GC), however, remains unclear. We investigated whether AA-associated molecular changes may contribute to GC through altered nucleotide metabolism. Integration of CTD, MSigDB, and…

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