Publication
A pro-inflammatory metastasis-associated macrophage subset induces tumor-promoting mesothelial cell conversion in ovarian cancer via IL-1α secretion.
Sophie Heidemann, Florian Finkernagel, Anna Mary Steitz, Julie Koennecke, Franziska Werner, Vanessa M Beutgen, Witold Szymanski, Johannes Graumann, Julia Teply-Szymanski, Andrea Nist, Thorsten Stiewe, Corinna U Keber, Niklas Gremke, Uwe Wagner, Carsten Denkert, María Gómez-Serrano, Elke Pogge von Strandmann, Rolf Müller, Silke Reinartz
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- PubMed
- Retrieved
- Sep 18, 2026
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- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260918-000001
Abstract
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Tumor-associated macrophages (TAMs) are key regulators of the tumor microenvironment, yet the functional specialization of TAM subsets in metastatic progression remains incompletely defined. Here, we characterized distinct TAM populations contributing to tumor-promoting mesothelial cell conversion…
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Candidate 1
- cancerMalignant Ovarian Neoplasmdictionary0.60
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