Publication
CFTR modulation alter pancreatic cancer cell growth and signaling: implications for cancer risk in cystic fibrosis.
Yunxia O'Malley, Henry Keen, Ian M Thornell, Zachary Campbell, Anna J Prouty, Carlos H F Chan, Andrew W Norris, Prabhat Goswami, Aliye Uc
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- PubMed
- Retrieved
- Sep 16, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260916-000001
Abstract
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BACKGROUND: People with cystic fibrosis (PwCF) have an increased risk of pancreatic cancer, likely related to chronic pancreatic inflammation and CFTR dysfunction. With the widespread use of CFTR modulators such as elexacaftor/tezacaftor/ivacaftor (ETI), understanding their impact on pancreatic…
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- cancerMalignant Pancreatic Neoplasmdictionary0.60
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