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Deep learning-based CT model for non-invasive prediction of tertiary lymphoid structures in pancreatic cancer: a multicenter study with prospective validation in an immunochemotherapy cohort.

Haopeng Yu, Xiaoying Li, Xuan Cheng, Yan Deng, Yuqi Wang, Yu Li, Bingjie Liu, Zixing Huang, Dan Cao

Journal for immunotherapy of cancerSep 12, 2026PMID 42731878doi:10.1136/jitc-2026-015705 Journal ArticleMulticenter StudyValidation StudypubmedProvenance
Source
PubMed
Retrieved
Sep 16, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260916-000001
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BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies. Tertiary lymphoid structures (TLS) have emerged as key components of the tumor immune microenvironment, associated with improved survival and enhanced immunotherapy response. However, non-invasive…

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