Publication
Lack of tumor-derived LCN2 sensitizes pancreatic cancer cells to ferroptosis induction.
Valentina Pita-Grisanti, Kristyn Gumpper-Fedus, Claire Cornellier, Hsiang-Yin Hsueh, Grace Vulic, Zachary Hurst, Ericka Velez-Bonet, Kaylin Chasser, Olivia Harder, Andrew J Gunderson, Stacey Culp, Maciej Pietrzak, Amy Webb, Thais F Bartelli, Florencia McAllister, Zobeida Cruz-Monserrate
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- PubMed
- Retrieved
- Sep 16, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260916-000001
Abstract
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Lipocalin 2 (LCN2) is upregulated in many cancers, including pancreatic ductal adenocarcinoma (PDAC), and contributes to tumor development. LCN2 regulates microbial composition, which can influence PDAC outcomes, and has been implicated in ferroptosis resistance in several cancer types. However,…
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Candidate 1
- cancerMalignant Pancreatic Neoplasmdictionary0.60
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