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Role of CircRNA_0005075 in gastric cancer immune evasion through regulation of lactate metabolic reprogramming and histone lactylation.

Jiaming Wu, Jin Jiang, Cong Chen, Guangjian Dou, Liyong Huang, Yi Zhu, Xiaoping Shen, Jie Chen

Translational oncologySep 12, 2026PMID 42731419doi:10.1016/j.tranon.2026.103037 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 16, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260916-000001
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PURPOSE: Gastric cancer remains one of the most lethal malignancies worldwide. While immune checkpoint inhibitors targeting the PD-1/PD-L1 axis have significantly advanced the treatment of advanced gastric cancer, their efficacy exhibits marked heterogeneity among patients, with a substantial…

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