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Is postoperative adjuvant therapy necessary for esophageal cancer patients with pathological complete response after neoadjuvant treatment?

Zi An Zhang, Jun Feng Liu, Jun Hong Liu, Shao Wei Zhang

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical OncologySep 10, 2026PMID 42731259doi:10.1016/j.ejso.2026.112120 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 26, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260926-000001
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BACKGROUND: Current National Comprehensive Cancer Network (NCCN) guidelines recommend omission of adjuvant therapy in esophageal cancer patients achieving pathological complete response (pCR) following neoadjuvant treatment. However, 20-40% of these patients experience disease recurrence,…

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