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Efficacy and safety of liposomal irinotecan plus nimotuzumab in immune checkpoint inhibitor-refractory recurrent or metastatic nasopharyngeal carcinoma: a single-arm, open-label, phase II trial.

Shuiqing He, Wei-Xin Bei, Nian Lu, Ze-Yu Zhao, Yanfang Ye, Chunyan Chen, Linquan Tang, Liting Liu, Shuhui Lv, Yan-Qun Xiang, Lin Wang

EClinicalMedicineSep 1, 2026PMID 42729623doi:10.1016/j.eclinm.2026.104170 PMC13562403Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 18, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260918-000001
Published

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BACKGROUND: Patients with recurrent or metastatic nasopharyngeal carcinoma (R/M NPC) who progress after immune checkpoint inhibitor (ICI) therapy have limited treatment options and poor outcomes. We evaluated the efficacy and safety of liposomal irinotecan plus nimotuzumab in patients with…

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Registered trialsNCT06414577

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