Publication
Tumor-derived CTHRC1 mediates ITGB3-dependent osteoclast differentiation to promote prostate cancer bone metastasis.
Tao Xie, Tianming Peng, Qu Li, Mingzhao Li, Maoping Cai, Qianyi Li, Yu-Zhong Yu, Jiehui Zhong, Chong Wang, Ming-Kun Chen, Zhe-Sheng Chen, Xian-Lu Song, Di Gu, Shan-Chao Zhao
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- PubMed
- Retrieved
- Sep 13, 2026
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- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260913-000001
Abstract
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Bone metastasis is a leading cause of mortality in advanced prostate cancer (PCa), with limited therapeutic options. This study investigates the molecular mechanisms underlying PCa bone metastasis and identifies potential therapeutic targets. Using in vitro co-culture systems and in vivo mouse…
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Candidate 1
- cancerMalignant Prostate Neoplasmdictionary0.60
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