Publication
4D nucleome landscape reveals dissolution of bipartite active X chromosome in liver cancer development.
Xiaoli Xie, Delin Tan, Jingyun Mo, Yang Xu, Qingqiang Ni, Ting Liu, Huaiming Wang, Bingjie Chen, Yujia Liao, Yingnan Lin, Wanting Chen, Susu Luo, Qing Fang, Menglan Zhao, Yangyinhui Yu, Cunjing Zheng, Ruolin Cui, Jiaying Wang, Hong Chang, Qing Gong, Alfred Sze-Lok Cheng, Huiqing Jiang, Tingting Li, Jia Wang
- Source
- PubMed
- Retrieved
- Sep 19, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260919-000001
Abstract
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Changes of three-dimensional chromosome organization in cancers are well established, but little focus has been placed on the behaviour of X chromosome (chrX). Here we show that hepatic chrX of male mice exhibits chromosome segregation, which is attenuated during hepatocellular carcinoma (HCC)…
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- cancerMalignant Liver Neoplasmdictionary0.60
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