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NCACC maps cross-sample spatial niches and reveals cIgG+ epithelial rare cells driving liver cancer invasion.

Cheng Hai, Yibo Hou, Siyang Yu, Xiaoyu Pan, George Michael Nicolas, Pengcheng Li, Canyucel Gungor, Tianying Yuan, Zhongfu Wang, Zitian Wang, Peter Edward Lobie, Shaohua Ma

GutSep 11, 2026PMID 42728030doi:10.1136/gutjnl-2026-338471 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 19, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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BACKGROUND: Liver cancer exhibits profound spatial and cellular heterogeneity, contributing to tumour progression, invasion and therapeutic resistance. Emerging evidence suggests that rare low-abundance malignant cell populations residing within discrete tissue niches influence these processes.…

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