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Ginsenoside Rg2 inhibit the cell viability of cisplatin-resistant epithelial ovarian cancer by suppressing CACNA1G-mediated calcium signaling.

Han Chen, Jiayi Wan, Siwen Lv, Chuanxiang Yao, Ye Tong, Xiutian Peng, Huiwen Wang, Siyuan Hou, Biqing Wu, Yinping Jin, Jiazhe Song, Kai Xue

Toxicology and applied pharmacologySep 11, 2026PMID 42727823doi:10.1016/j.taap.2026.118031 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 17, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260917-000001
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Most patients with epithelial ovarian cancer (EOC) treated with cisplatin (cDDP) ultimately develop resistance. Owing to its anti-tumor effects and low toxicity, ginsenoside Rg2 (G-Rg2) is regarded as a potential active compound for the chemotherapy of EOC. By leveraging expression profiles of…

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