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Differential effects of BCG-Russia and BCG-TICE on trained immunity: Potential implications for bladder cancer immunotherapy.

Richard W Nauman, Peter A Greer, Andrew W Craig, Tiziana Cotechini, D Robert Siemens, Charles H Graham

PloS oneJan 1, 2026PMID 42726801doi:10.1371/journal.pone.0357950 PMC13567787Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 19, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260919-000001
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In recent years, immunotherapy of patients with higher-risk non-muscle invasive bladder cancer (NMIBC) in North America has relied on the use of the TICE strain of BCG. However, limitations in the supply chain have warranted investigation of the therapeutic benefit of other strains of BCG, such as…

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